Cardiovascular disease risk factor response to a sustained carbohydrate restriction

Sustained carbohydrate restriction used for reversing type 2 diabetes also lowered risk factors for Cardiovascular disease. 

Published May 1, 2018


A continuous care treatment including nutritional ketosis in patients with type 2 diabetes improved most biomarkers of CVD risk after 1 year. The increase in LDL-cholesterol appeared limited to the large LDL subfraction. LDL particle size increased, total LDL-P and ApoB were unchanged, and inflammation and blood pressure decreased.


Cardiovascular disease (CVD) is a leading cause of death among adults with type 2 diabetes mellitus (T2D). We recently reported that glycemic control in patients with T2D can be significantly improved through a continuous care intervention (CCI) including nutritional ketosis. The purpose of this study was to examine CVD risk factors in this cohort.

Direct Link to the peer review